User Tools

Site Tools


til_2022

Table of Contents

2022-04-22

2022-02-23

  • In 2000, the United States Food and Drug Administration (FDA) established an online registry for the details of clinical trials. The FDA required that scientists who were studying therapies for serious diseases needed to provide some details of their study designs and the outcomes that they planned to investigate. This requirement reduced the bias towards positive findings in published research. We see evidence of this in the chart, showing clinical trials funded by the National Heart, Lung and Blood Institute (NHLBI), which adopted this requirement. Before 2000 – when pre-registration of studies was not required – most candidate drugs to treat or prevent cardiovascular disease showed large benefits. But most trials published after 2000 showed no benefit.
    https://ourworldindata.org/randomized-controlled-trials#preregistration-allows-us-to-hold-researchers-accountable-to-their-original-study-plans

2022-02-01

til_2022.txt · Last modified: 2022/04/22 16:57 by raju